Meta-analysis of calcium
only trials
15 eligible trials only 5 with adequate data
8151 participants median follow-up 3.6 years
Outcomes
Myocardial Infarction HR 1.31 [95% CI 1.02, 1.67]
Stroke HR 1.20 [95% CI
0.96, 1.5]
Composite end point HR 1.18 [95% CI 1.00, 1.39] p =
0.057
Analysis of other trials 11,921 participants;
Calcium recipients
pooled
Myocardial Infarction HR 1.27 [95% CI 1.01, 1.59] p =
0.038
However, only 3% of NHS prescribed calcium is without
vit D!
Take away message: dont give calcium by itself